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Notifiable conditions and laboratory packages
95 rows. 60 have a starter laboratory package. 35 are on the national list with no package in this registry yet. This is the CDC 2025 notification protocol, the 2026 additions (Oropouche and COVID-19-associated pediatric mortality), and the methods a public health laboratory already runs. It is not ICD-11.
Showing 95 of 95
Immediate, extremely urgent | Within 4 hours if the source is unrecognized, illness is severe, or release is suspected. Within 24 hours for treated naturally occurring or occupational disease. | BANT | 33675-3 | 21927003, 260415000, 10828004, 260373001 | US Core Lab + ORU^R01 |
|---|---|---|---|---|---|
Immediate, extremely urgent | Within 4 hours for foodborne (except endemic Alaska), suspected intentional release, infant clusters, and unknown etiology. Routine for sporadic infant and wound cases. | BOTOX | 43409-2 | 113862002, 260415000, 10828004, 260373001 | US Core Lab + ORU^R01 |
Immediate, extremely urgent | Within 4 hours if intentional release is suspected. Routine for other cases, still before final classification. | YPES | 33676-1 | 54365000, 260415000, 10828004, 260373001 | US Core Lab + ORU^R01 |
Immediate, extremely urgent | Within 4 hours. All cases, before classification. | Not published | None published | None published | No message until a package exists |
Immediate, extremely urgent | Within 4 hours. Confirmed and probable cases. | Not published | None published | None published | No message until a package exists |
Immediate, extremely urgent | Within 4 hours if intentional release is suspected (confirmed, probable, and suspected). Routine for other confirmed and probable cases. | FTUL | 43406-8 | 15017006, 260415000, 10828004, 260373001 | US Core Lab + ORU^R01 |
Immediate, extremely urgent | Within 4 hours if intentional release is suspected. Within 24 hours for other suspected and confirmed cases. | Not published | None published | None published | No message until a package exists |
Immediate, urgent | Within 24 hours for temporally or spatially clustered cases. Routine for other confirmed and probable cases. | BRUC | 43407-6 | 78007006, 260415000, 10828004, 260373001 | US Core Lab + ORU^R01 |
Immediate, urgent | Within 24 hours. Confirmed and probable cases. | Not published | None published | None published | No message until a package exists |
Immediate, urgent | Within 24 hours. Confirmed cases. | Not published | None published | None published | No message until a package exists |
Immediate, urgent | Within 24 hours. Confirmed and probable cases. | FLUSUB, H5RNA, FLU-WGS | 95941-1, 49524-2, 55465-9, 68986-9, 96746-5, 96747-3, 96748-1, 96749-9 | 442696006, 260373001, 260415000, 419984006, 407479009, 30714006, 131196009 | US Core Lab + ORU^R01 |
Immediate, urgent | Within 24 hours. Confirmed cases. | MEAS | 49526-7 | 14189004, 260373001, 260415000, 419984006 | US Core Lab + ORU^R01 |
Immediate, urgent | Within 24 hours. Confirmed and probable cases. | BURK | 43408-4 | 48815003, 260415000, 10828004, 260373001 | US Core Lab + ORU^R01 |
Immediate, urgent | Within 24 hours. Confirmed and probable cases. | MPOX, MPOX-WGS | 100434-0, 99770-0, 99771-8 | 424206003, 260373001, 260415000, 419984006, 30714006, 131196009 | US Core Lab + ORU^R01 |
Immediate, urgent | Within 24 hours. Confirmed cases. | Not published | None published | None published | No message until a package exists |
Immediate, urgent | Within 24 hours. Confirmed cases. | Not published | None published | None published | No message until a package exists |
Immediate, urgent | Within 24 hours for imported animals, a new geographic variant, or a new reservoir species. Other positive and required negative results are routine, at least monthly. | Not published | None published | None published | No message until a package exists |
Immediate, urgent | Within 24 hours. Confirmed cases. | Not published | None published | None published | No message until a package exists |
Immediate, urgent | Within 24 hours for confirmed rubella. Congenital rubella syndrome is routine, confirmed cases. | RUBELLA | 49528-3, 5334-8 | 36653000, 260373001, 260415000, 419984006, 10828004, 260385009, 42425007 | US Core Lab + ORU^R01 |
Routine national notification | Routine. Confirmed and probable cases. | TICK-PCR | 94658-2, 42533-0, 42534-8, 42535-5 | 103554005, 260373001, 260415000, 419984006 | US Core Lab + ORU^R01 |
Routine national notification | Routine. Confirmed and probable cases. | TICK-PCR | 94658-2, 42533-0, 42534-8, 42535-5 | 103554005, 260373001, 260415000, 419984006 | US Core Lab + ORU^R01 |
Routine national notification | Routine. Confirmed and probable cases. | TICK-PCR | 94658-2, 42533-0, 42534-8, 42535-5 | 103554005, 260373001, 260415000, 419984006 | US Core Lab + ORU^R01 |
Routine national notification | Routine arboviral notification. Confirmed and probable, neuroinvasive and non-neuroinvasive. | WNVIGM | 31797-7 | 57311007, 10828004, 260385009, 42425007 | US Core Lab + ORU^R01 |
Routine national notification | Routine arboviral notification. Confirmed and probable cases. | EEERNA | 35359-4 | 58225009, 260373001, 260415000, 419984006 | US Core Lab + ORU^R01 |
Routine national notification | Routine arboviral notification. Confirmed and probable cases. | POWV | 94659-0, 94660-8 | 84196001, 260373001, 260415000, 419984006, 10828004, 260385009, 42425007 | US Core Lab + ORU^R01 |
Routine national notification | Routine. Confirmed, probable, and suspected. Includes dengue, severe dengue, and dengue-like illness. | TRIPLEX | 81154-7, 79190-5 | 260373001, 260415000, 419984006 | US Core Lab + ORU^R01 |
Routine national notification | Routine arboviral notification. Confirmed and probable cases. | TRIPLEX | 81154-7, 79190-5 | 260373001, 260415000, 419984006 | US Core Lab + ORU^R01 |
Routine national notification | Routine. Confirmed and probable, congenital and non-congenital. | ZIKV, TRIPLEX | 79190-5, 81154-7 | 50471002, 260373001, 260415000, 419984006, 42425007 | US Core Lab + ORU^R01 |
Routine national notification | Routine. Confirmed and probable cases. | Not published | None published | None published | No message until a package exists |
Routine national notification | Routine. Confirmed and probable cases. Case definition revised for 2026 (CSTE 25-ID-02). | CAMP-PCR, CAMP-WGS | 82311-2, 82312-0, 96565-9, 96566-7, 96567-5 | 66543000, 260373001, 260415000, 419984006, 40980006, 30714006, 131196009 | US Core Lab + ORU^R01 |
Routine national notification | Routine. Confirmed clinical cases and confirmed screening cases are both notifiable. | CAURISCode conflict, see note | 94657-4, 564-4 | 712986001, 260373001, 260415000, 419984006, 52101004, 2667000 | US Core Lab + ORU^R01 |
Routine national notification | Routine. Confirmed clinical cases and confirmed screening cases. | CPO, CRE-KPN, CRAB, CRPA, CRPA-WGSCode conflict, see note | 85502-3, 85503-1, 85504-9, 85824-1, 96568-3, 85501-5, 96750-7 | 260373001, 260415000, 419984006, 56415008, 717145007, 717146008, 717148009, 717149001, 717147004, 59714003, 52499004, 30714006, 131196009 | US Core Lab + ORU^R01 |
Routine national notification | Routine. Confirmed cases. | CTNG | 6349-5, 6356-0 | 63938009, 260373001, 260415000, 419984006 | US Core Lab + ORU^R01 |
Routine national notification | Routine. Confirmed and probable cases. | CTNG | 6349-5, 6356-0 | 63938009, 260373001, 260415000, 419984006 | US Core Lab + ORU^R01 |
Routine national notification | Routine. Confirmed cases from high- and low-incidence jurisdictions. Probable cases from low-incidence jurisdictions only. | COCCI | 48426-1, 48427-9, 48428-7 | 47717005, 10828004, 260385009, 42425007, 11214006, 131194007 | US Core Lab + ORU^R01 |
Routine national notification | Routine. Confirmed and probable cases. | STEC, STEC-WGS | 33675-3, 33676-1, 96559-2, 96560-0, 96561-8, 96562-6, 96563-4, 96564-2 | 1173630008, 260373001, 260415000, 419984006, 112283007 | US Core Lab + ORU^R01 |
Routine national notification | Routine. Confirmed and probable cases. | STEC, STEC-WGS | 33675-3, 33676-1, 96559-2, 96560-0, 96561-8, 96562-6, 96563-4, 96564-2 | 1173630008, 260373001, 260415000, 419984006, 112283007 | US Core Lab + ORU^R01 |
Routine national notification | Routine. Outbreaks as the jurisdiction defines them. | GIPANEL, ENTC, NORO, ROTA | 79381-0, 6463-4, 72944-2, 72945-9, 72946-7, 6554-0, 82313-8 | 260373001, 260415000, 419984006, 27268008, 4980008, 66543000, 113861009, 19034005, 10828004, 260385009, 42425007 | US Core Lab + ORU^R01 |
Routine national notification | Routine. Confirmed and probable cases. | LIST-WGS | 96557-6, 94653-3, 94187-4 | 44814009, 260373001, 260415000, 419984006 | US Core Lab + ORU^R01 |
Routine national notification | Routine. Confirmed and probable cases. | SALM-WGS, GIPANEL | 96556-8, 94653-3, 85504-9, 79381-0 | 27268008, 30714006, 131196009, 260373001, 260415000, 419984006 | US Core Lab + ORU^R01 |
Routine national notification | Routine. Confirmed and probable cases. | SALM-WGS | 96556-8, 94653-3, 85504-9 | 27268008, 30714006, 131196009 | US Core Lab + ORU^R01 |
Routine national notification | Routine. S. enterica serotypes Paratyphi A, B (tartrate negative), and C. | SALM-WGS | 96556-8, 94653-3, 85504-9 | 27268008, 30714006, 131196009 | US Core Lab + ORU^R01 |
Routine national notification | Routine. Confirmed and probable cases. | SHIG-WGS | 96558-4, 85504-9 | 4980008, 30714006, 131196009 | US Core Lab + ORU^R01 |
Routine national notification | Routine. Confirmed cases. | VIB-PCR | 94654-1, 94655-8, 94656-6 | 47715002, 260373001, 260415000, 419984006 | US Core Lab + ORU^R01 |
Routine national notification | Routine. Confirmed and probable cases. | VIB-PCR | 94654-1, 94655-8, 94656-6 | 47715002, 260373001, 260415000, 419984006 | US Core Lab + ORU^R01 |
Routine national notification | Routine. Acute and chronic: confirmed and probable. Perinatal: confirmed and probable. | HEPB | 5196-1, 42595-9 | 66071002, 11214006, 131194007 | US Core Lab + ORU^R01 |
Routine national notification | Routine. Acute and chronic: confirmed and probable. Perinatal: confirmed. | HEPC | 40726-2, 11011-4 | 50711007, 11214006, 131194007 | US Core Lab + ORU^R01 |
Routine national notification | Routine. Confirmed HIV infection, and perinatally exposed infants before classification. | HIV12 | 56888-1 | 86406008, 11214006, 131194007 | US Core Lab + ORU^R01 |
Routine national notification | Routine. Confirmed cases. | LEGION | 14300-8, 43398-7 | 42323005, 10828004, 260385009, 42425007, 260373001, 260415000, 419984006 | US Core Lab + ORU^R01 |
Routine national notification | Routine. High-incidence jurisdictions report probable and suspect. Low-incidence jurisdictions also report confirmed. | LYME | 48421-2, 48422-0, 48423-8 | 47447000, 10828004, 260385009, 42425007 | US Core Lab + ORU^R01 |
Routine national notification | Routine on the 2025 protocol. Confirmed and probable cases. Many states still want a same-day call. | MENING | 43405-0, 79383-6 | 243573003, 260373001, 260415000, 419984006 | US Core Lab + ORU^R01 |
Routine national notification | Routine. Confirmed and probable cases. | MUMPS | 49527-5 | 243572008, 260373001, 260415000, 419984006 | US Core Lab + ORU^R01 |
Routine national notification | Routine, all cases before classification. Infant exposures are treated as urgent by most states. | PERT | 31948-6, 31949-4 | 73815006, 260373001, 260415000, 419984006 | US Core Lab + ORU^R01 |
Routine national notification | Routine. Primary and secondary: confirmed and probable. Early non-primary non-secondary, unknown duration, and late: probable. Congenital: confirmed and probable. | SYPH | 24111-7, 31147-2, 24112-5 | 8165007, 11214006, 131194007 | US Core Lab + ORU^R01 |
Routine national notification | Routine. Confirmed cases. Counts are published quarterly, not in the weekly table. | MTBPCR, AFBSMR, MTB-DR, MTB-WGS | 38379-4, 11477-7, 88162-3, 88163-1, 88164-9, 88165-6, 88166-4, 88167-2, 96569-1, 88168-0, 88169-8, 88170-6, 88171-4, 88172-2 | 113861009, 260373001, 260415000, 419984006, 243365003, 260385009, 113858008, 30714006, 131196009 | US Core Lab + ORU^R01 |
Routine national notification | Routine. Confirmed cases. | RESP4, FLUSUB | 95941-1, 92142-9, 92141-1, 94500-6, 40988-8, 49524-2, 55465-9, 68986-9 | 260373001, 260415000, 419984006, 442696006 | US Core Lab + ORU^R01 |
Routine national notification | Routine. All outbreaks. | DW-COLI, BEACH-ENT, LEGION | 41144-7, 41145-4, 59463-0, 14300-8, 43398-7 | 112283007, 52101004, 2667000, 113824003, 42323005, 10828004, 260385009, 42425007, 260373001, 260415000, 419984006 | US Core Lab + ORU^R01 |
Routine national notification | Routine. Confirmed and probable cases. | Not published | None published | None published | No message until a package exists |
Routine national notification | Routine. Confirmed and probable cases. | Not published | None published | None published | No message until a package exists |
Routine national notification | Routine. Confirmed and probable cases. | Not published | None published | None published | No message until a package exists |
Routine national notification | Routine. Confirmed and probable cases. | Not published | None published | None published | No message until a package exists |
Routine national notification | Routine. All cases before classification. | Not published | None published | None published | No message until a package exists |
Routine national notification | Routine. Confirmed and probable cases. | Not published | None published | None published | No message until a package exists |
Routine national notification | Routine. Confirmed cases. | Not published | None published | None published | No message until a package exists |
Routine national notification | Routine. Confirmed cases. | Not published | None published | None published | No message until a package exists |
Routine national notification | Routine. Confirmed and probable cases. | Not published | None published | None published | No message until a package exists |
Routine national notification | Routine. Confirmed cases. | Not published | None published | None published | No message until a package exists |
Routine national notification | Routine. Confirmed and probable cases. | Not published | None published | None published | No message until a package exists |
Routine national notification | Routine. Confirmed and suspected cases. | Not published | None published | None published | No message until a package exists |
Routine national notification | Routine. Confirmed and probable cases. | Not published | None published | None published | No message until a package exists |
Routine national notification | Routine. Confirmed and probable cases. | Not published | None published | None published | No message until a package exists |
Routine national notification | Routine. Confirmed and probable cases. | Not published | None published | None published | No message until a package exists |
Routine national notification | Routine. Confirmed VISA and VRSA. | Not published | None published | None published | No message until a package exists |
Routine national notification | Routine. Confirmed and probable cases. | Not published | None published | None published | No message until a package exists |
Routine national notification | Routine. All cases before classification. | Not published | None published | None published | No message until a package exists |
Routine national notification | Routine. Confirmed and probable cases. | Not published | None published | None published | No message until a package exists |
Routine national notification | Routine. All cases before classification. | Not published | None published | None published | No message until a package exists |
Routine national notification | Routine. Confirmed and probable cases. | Not published | None published | None published | No message until a package exists |
Routine national notification | Routine. Confirmed and probable cases. | Not published | None published | None published | No message until a package exists |
Routine national notification | Routine. Confirmed cases, at least annually. | Not published | None published | None published | No message until a package exists |
Routine national notification | Routine. Definite, probable, possible, and suspicious cases. Occupational and non-occupational. | Not published | None published | None published | No message until a package exists |
Routine national notification | Routine. Confirmed cases. | Not published | None published | None published | No message until a package exists |
2026 national notification | Nationally notifiable beginning 2026. Event code 11069. CSTE 25-ID-03. | COV2, RESP4, SC2-WGS | 95941-1, 94500-6, 92142-9, 92141-1, 40988-8, 96741-6, 96742-4, 96743-2, 96744-0 | 840533007, 260373001, 260415000, 419984006 | US Core Lab + ORU^R01 |
2026 national notification | Nationally notifiable beginning 2026. Non-congenital event 50290. Congenital event 50291. | OROV | 100383-8 | 59881000, 260373001, 260415000, 419984006 | US Core Lab + ORU^R01 |
Laboratory methods | Not nationally notifiable as a case condition for 2025 onward. Pediatric mortality is the 2026 exception. | COV2, SC2-WGS, WWRESP | 95941-1, 94500-6, 96741-6, 96742-4, 96743-2, 96744-0, 96896-8, 92142-9 | 840533007, 260373001, 260415000, 419984006 | US Core Lab + ORU^R01 |
Laboratory methods | Not the same condition as VISA or VRSA. | MECA | 48813-0 | 115329001, 260373001, 260415000, 419984006 | US Core Lab + ORU^R01 |
Laboratory methods | Not a notifiable condition by itself. | MICPANEL | 50545-3 | 131196009, 264841006, 30714006 | US Core Lab + ORU^R01 |
Laboratory methods | Not nationally notifiable. State HAI rules vary. | VRE | 43402-7, 43403-5, 43404-3 | 113824003, 260373001, 260415000, 419984006 | US Core Lab + ORU^R01 |
Laboratory methods | Report the identified organism when that organism is notifiable. A negative run is not a negative for every pathogen. | MNGS | 94187-4 | 260415000, 260373001 | US Core Lab + ORU^R01 |
Laboratory methods | Not on the 2025 national notification protocol. Some states require it. | HISTO | 48424-6 | 53930006, 10828004, 260385009, 42425007 | US Core Lab + ORU^R01 |
Laboratory methods | Not on the 2025 national notification protocol. Some states require it. | BLASTO | 48425-3 | 73816007, 10828004, 260385009, 42425007 | US Core Lab + ORU^R01 |
Laboratory methods | Not nationally notifiable. Clinically urgent for the ordering physician. | CRYPTO | 29910-7 | 52498007, 10828004, 260385009, 42425007 | US Core Lab + ORU^R01 |
Laboratory methods | Compliance testing, not the blood-lead notification. | LEAD-DW | 5690-3 | None published | US Core Lab + ORU^R01 |
Laboratory methods | Revised Total Coliform Rule. Not a patient notifiable condition. | DW-COLI | 41144-7, 41145-4 | 112283007, 52101004, 2667000 | US Core Lab + ORU^R01 |
Laboratory methods | Beach-action decisions. Not a patient notifiable condition. | BEACH-ENT | 59463-0 | 113824003 | US Core Lab + ORU^R01 |

Share what you build.
Anything that takes a lab real work to get right is worth not rebuilding. Salus makes the work portable.
Test definitions
A full test with its acceptable result set, reference ranges, and LOINC/SNOMED coding, ready to run.
Result sets
Coded, validated result sets and interpretive rules that other labs can adopt as-is or adapt.
Accessioning workflows
Intake, routing, and processing workflows proven in one lab, packaged for another.
Report templates
Final, corrected, and case-report templates, so a lab does not redesign what already works.
How it works.
Publish, adopt, vet, and earn. A virtuous cycle that gets stronger as more labs join.
Publish
A lab packages a test definition, workflow, or template as a versioned bundle and publishes it to the registry, with attribution.
Adopt
Any lab can browse, install, and import a bundle into its own environment, then adapt it to local needs.
Vet
Because this is clinical content, an approval gate lets a lab review and sign off on a bundle before it is used in production.
Credit
When another lab incorporates a producer's content into its lab, the producer earns credits.
We pay it forward to the labs that give back.
Good content should be rewarded. When a lab adopts a test definition, workflow, or report template you published, and puts it to use, you earn credits. The more your work is incorporated across the community, the more you earn.
Credits translate directly into things a public health lab values, so contributing to the commons lowers your own cost of running on Salus.
- Free professional-services hours
- Hosting and cloud-resource allowances
- Platform usage credit
Safe to adopt, by design.
- Every bundle is versioned, so a lab knows exactly what it is adopting and can pin or upgrade deliberately.
- An approval gate lets a lab review and sign off on shared clinical content before it is used in production.
- Producers keep attribution, so the labs that build the best content are recognized for it.
- Free and open: the content commons belongs to the public health community, under community governance.
Join the public health content commons.
The first labs to publish set the standard the rest of the community builds on.