Library
BiothreatLRN · Laboratory Response NetworkBANTSelect-agent rule-out pack
Bacillus anthracis (LRN rule-out)
Bacillus anthracis
Last reviewed 2026-08-13
Public health significance
A rule-out is a public-health product. The custody trail is part of the result.
Specimen types
As directed by the LRN protocol
Method
LRN rule-out / rule-in
CLIA / validation
LRN protocols and LDT/reference methods. Biosafety level is not optional.
Interpretation
Not detected / ruled out, Presumptive, Confirmed. Never collapse those three into Positive.
Reflex / referral
Referral to the LRN reference laboratory on presumptive. Law enforcement notification per protocol.
Quality control
LRN-specified controls. Document chain of custody on every handoff.
Reportability
Immediate. Not a next-batch ELR item.
HL7 / ELR
Follow APHL/CDC LRN messaging. Routine ELR is not sufficient by itself.
Sources
CDC LRN; APHL biothreat bench cards.