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Epidemic potentialMOL · MolecularTRIPLEXArboviral surveillance pack
Dengue + Chikungunya + Zika RNA panel
Dengue, Chikungunya, Zika
Last reviewed 2026-08-13
Public health significance
Travel-associated arboviruses plus expanding Aedes range. One panel, three public-health decisions.
Specimen types
Serum, CSF; urine additional for Zika
Method
Trioplex-style multiplex RNA
CLIA / validation
High complexity multiplex. Validate each virus and each specimen type you will report.
Interpretation
Detected / Not detected per virus. Serology and PRNT still close many cases.
Reflex / referral
IgM / PRNT when RNA is negative and timing suggests antibody is the right window.
Quality control
Virus-specific positives. Watch primer updates as lineages shift.
Reportability
Locally acquired dengue or Zika is an immediate epi event in most states.
HL7 / ELR
Panel 81154-7 in OBR-4. Zika RNA often 79190-5 in its own OBX.
Sources
CDC arboviral diagnostic testing guidance; LOINC 81154-7.